Analisis Faktor-Faktor Risiko Kejadian Dislipidemia pada Karyawan Pria Head Office PT.X, Cakung, Jakarta Timur
Abstract
Abstrak
Kejadian dislipidemia di Indonesia merupakan salah satu masalah kesehatan masyarakat yang prevalensinya semakin meningkat dari tahun ke tahun, tak terkecuali pada para karyawan. Tidak diragukan lagi bahwa dislipidemia yang tidak terdeteksi dan tertangani dengan baik dapat meningkatkan risiko aterosklerosis yang dapat menyebabkan penyakit jantung dan pembuluh darah dan berujung pada kematian. Penelitian ini bertujuan untuk mengetahui faktor-faktor risiko yang berhubungan dengan kejadian dislipidemia. Penelitian yang dilakukan pada sebuah perusahaan alat berat di Cakung, Jakarta Timur ini menggunakan desain studi cross sectional dan metode simple random sampling dengan jumlah sampel sebanyak 93 orang pria berusia 25-55 tahun. Hasil penelitian menunjukkan bahwa 80,6% responden mengalami dislipidemia. Terdapat hubungan bermakna antara asupan karbohidrat (OR=10,8 95% CI 1,2-95,4), usia (OR=1,7 95% CI 0,5-5,6), IMT (OR=3,9 95% CI 0,7-21,9 ), lingkar pinggang (OR=2,3 95% CI 0,6-8,4), dan hipertensi (OR=1,5 95% CI 0,4-6,7) terhadap kejadian dislipidemia. Asupan karbohidrat merupakan faktor risiko paling dominan setelah dikrontrol oleh variabel usia, IMT, lingkar pinggang dan hipertensi.
Kata Kunci : Dislipidemia; faktor risiko; karyawan; pria.
Abstract
Dyslipidemia is a public health problem in Indonesia which prevalence is increasing every year, including in workers. It is established that undetected and untreated dyslipidemia increases the risk of atherosclerosis that causes cardiovascular diseases and leads to death. Â The objective of this study was to identify risk factors associated with dyslipidemia. This study was conducted a heavy equipment company located in Cakung, East Jakarta using cross sectional design and simple random sampling method with 93 men aged 25-55 years old. The result showed that 80,6% of respondents suffered from dyslipidemia. There were significant associations between carbohydrate intake (OR=10,8 95% CI 1,2-95,4), age (OR=1,7 95% CI 0,5-5,6), Body Mass Index (BMI) (OR=3,9 95% CI 0,7-21,9), waist circumference (OR=2,3 95% CI 0,6-8,4), and hypertension (OR=1,5 95% CI 0,4-6,7) with dyslipidemia in which carbohydrate intake was the most dominant risk factors after adjustment of multiple confounders.
Keywords : Dyslipidemia; risk factors; workers; men
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Kavey R-EW, Daniels SR, Lauer RM, Atkins DL, Hayman LL, Taubert K. American Heart Association Guidelines for Primary Prevention of Atherosclerotic Cardiovascular Disease Beginning in Childhood. AHA J. 2003;107(11):1562–6.
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002 Dec 17;106(25):3143–421.
Rahmawansa S. Sany. Dislipidemia sebagai Risiko Utama Penyakit Jantung Koroner (PJK). Cermin Dunia Kedokt 169. 2009;36(3):181–4.
Wong ND. Epidemiological studies of CHD and the evolution of preventive cardiology. Vol. 11, Nature Reviews Cardiology. Nature Publishing Group; 2014. p. 276–89.
Nelson RH. Hyperlipidemia as a Risk Factor for Cardiovascular Disease. Vol. 40, Primary Care - Clinics in Office Practice. 2013. p. 195–211.
Raal FJ. Pathogenesis and Management of the Dyslipidemia of the Metabolic Syndrome. Metab Syndr Relat Disord [Internet]. 2009 Apr [cited 2020 Jan 8];7(2):83–8. Available from: http://www.liebertpub.com/doi/10.1089/met.2008.0079
Halpern A, Mancini MC, Magalhães MEC, Fisberg M, Radominski R, Bertolami MC, et al. Metabolic syndrome, dyslipidemia, hypertension and type 2 diabetes in youth: From diagnosis to treatment. Vol. 2, Diabetology and Metabolic Syndrome. 2010.
High Cholesterol Facts | cdc.gov [Internet]. [cited 2020 Jan 10]. Available from: https://www.cdc.gov/cholesterol/facts.htm
Çetin İ, Yildirim B, Şahin Ş, Şahin İ, Etikan İ. Serum lipid and lipoprotein levels, dyslipidemia prevalence, and the factors that influence these parameters in a Turkish population living in the province of Tokat*. Turk J Med Sci. 2010;40(5):771–82.
Wang S, Xu L, Jonas JB, You QS, Wang YX, Yang H. Prevalence and Associated Factors of Dyslipidemia in the Adult Chinese Population. Federici M, editor. PLoS One [Internet]. 2011 Mar 10 [cited 2020 Jan 10];6(3):e17326. Available from: http://dx.plos.org/10.1371/journal.pone.0017326
Adam MJ, Soegono S, Semiardji G, Adriansyah H. Petunjuk Praktis Penatalaksanaan Dislipidemia. Jakarta: Pengurus Besar Perkumpulan Endokrinologi Indonesia (PB. PERKENI); 2004.
Departemen Kesehatan RI. Survey Kesehatan Nasional, Survey Kesehatan Rumah Tangga (SKRT) 2004. Jakarta; 2004.
Ministry of Health. Basic Health Survey. Jakarta; 2013.
Arsana PM, Rosandi R, Manaf A, Budhiarta A, Permana H, Sucipta K. Panduan Pengelolaan Dislipidemia di Indonesia. PB PERKENI, editor. Jakarta; 2015.
Subekti I. Pengelolaan Dislipidemia pada Tingkat Pelayanan Primer. Maj Kedokt Indones. 2005;55(3):285–6.
Workers and Chronic Conditions, Opportunities to Improves Productivity. Washington DC; 2000.
Zakiyah D. Faktor-Faktor Risiko yang berhubungan dengan Hipertensi dan Hiperlipidemia sebagai Faktor Risiko PJK diantara Pekerja di Kawasan Industri Pulo Gadung, Jakarta Timur Tahun 2006. Universitas Indonesia; 2008.
Rahmawati ND. Prevalensi Dislipidemia pada Perusahaan Alat Berat X di Wilayah Cakung, Jakarta Timur. Jakarta; 2013.
Estari M, Reddy AS, Bikshapathi T, Satyanarayana J, Venkanna L, Reddy MK. The investigation of serum lipids and prevalence of dyslipidemia in urban adult population of Warangal district, Andhra Pradesh, India [Internet]. Vol. 1, Biology and Medicine. 2009 [cited 2020 Jan 8]. Available from: www.biolmedonline.com
Gupta R, Misra A, Vikram NK, Kondal D, Gupta SS, Agrawal A, et al. Younger age of escalation of cardiovascular risk factors in Asian Indian subjects. BMC Cardiovasc Disord. 2009 Jul 5;9.
Jellinger PS, Smith DA, Mehta AE, Ganda O, Handelsman Y, Rodbard HW, et al. American association of clinical endocrinologists’ guidelines for management of dyslipidemia and prevention of atherosclerosis. Vol. 18, Endocrine Practice. 2012. p. 1–78.
Delavar M, Lye M, Hassan S, Khor G, Hanachi P. Physical activity, nutrition, and dyslipidemia in middle-aged women. Iran J Public Health [Internet]. 2011 Dec [cited 2020 Jan 9];40(4):89–98. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23113107
Pengkajian Status Gizi Studi Epidemiologi dan Penelitian Rumah Sakit Edisi Kedua. Jakarta: Balai Penerbit Fakultas Kedokteran Universitas Indonesia; 2010.
Te Morenga L, Montez JM. Health effects of saturated and trans-fatty acid intake in children and adolescents: Systematic review and meta-analysis. 2017 [cited 2020 Jan 9]; Available from: https://doi.org/10.1371/journal.pone.0186672
Supari F, Rachman OJ. Cholesterol-Lowering Effect of “Soluble Fiber†as an adjunct to “Low Calories Indonesian Diet†In Patients with Hypercholesterolemia. Vol. 11.
Howard B V, Ruotolo G, Robbins DC. Obesity and dyslipidemia. Endocrinol Metab Clin North Am [Internet]. 2003 Dec [cited 2020 Jan 9];32(4):855–67. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0889852903000732
Xu W, Hang J, Gao W, Zhao Y, Cao T, Guo L. Association between job stress and newly detected combined dyslipidemia among Chinese workers: findings from the SHISO study. J Occup Health [Internet]. 2011 [cited 2020 Jan 9];53(5):334–42. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21817833
Klein F, das Neves VJ, Costa R, Sanches A, Sousa T, Sampaio Moura MJC, et al. Dyslipidemia Induced by Stress. In: Dyslipidemia - From Prevention to Treatment. InTech; 2012.
Jeeyar, Hemalatha, Wilma DSC. Evaluation of effect of smoking and hypertension on serum lipid profile and oxidative stress. Asian Pacific J Trop Dis. 2011 Dec;1(4):289–91.
Tan XJ, Jiao GP, Ren YJ, Gao XR, Ding Y, Wang XR, et al. Relationship between smoking and dyslipidemia in western Chinese elderly males. J Clin Lab Anal. 2008;22(3):159–63.
Haj Mouhamed D, Ezzaher A, Neffati F, Gaha L, Douki W, Najjar MF. Association between cigarette smoking and dyslipidemia. Immuno-Analyse Biol Spec. 2013 Aug;28(4):195–200.
Widada NS. Analisis Hubungan Kebiasaan Merokok dengan Dislipidemia pada Pria yang Melakukan Medical Check Up di Jakarta Tahun 2002. Universitas Indonesia; 2002.
Iman S. Serangan Jantung dan Stroke Hubungannya dengan Lemak dan Kolesterol Edisi Kedua. Jakarta: PT. Gramedia Pustaka Utama.; 2004.
Holzmann MJ, Jungner I, Walldius G, Ivert T, Nordqvist T, Östergren J, et al. Dyslipidemia is a strong predictor of myocardial infarction in subjects with chronic kidney disease. Ann Med. 2012;44(3):262–70.
Madssen E, Laugsand LE, Wiseth R, Mørkedal B, Platou C, Vatten L, et al. Risk of acute myocardial infarction: Dyslipidemia more detrimental for men than women. Epidemiology. 2013;24(5):637–42.
Shigematsu K, Watanabe Y, Nakano H. Influences of hyperlipidemia history on stroke outcome; a retrospective cohort study based on the Kyoto Stroke Registry. BMC Neurol. 2015;15(1):1–6.
Wengrofsky P, Lee J, N. Makaryus A. Dyslipidemia and Its Role in the Pathogenesis of Atherosclerotic Cardiovascular Disease: Implications for Evaluation and Targets for Treatment of Dyslipidemia Based on Recent Guidelines. Dyslipidemia [Working Title]. 2019;
Sartika RAD. Pengaruh Asam Lemak Trans terhadap Profil Lipid Darah. Universitas Indonesia; 2007.
Hastiti LR. Pajanan PM2,5 dan Gangguan Fungsi Paru serta Kadar Profil Lipid Darah (HDL, LDL, Kolesterol Total, Trigliserida) pada Karyawan PT X, Kalimantan Selatan Tahun 2012. Universitas Indonesia; 2013.
Sunardjo MH. Prevalensi Dislipidemia dan Sebaran pada Beberapa Faktor Risiko Pekerja Laki-laki Perkantoran di PT. X. Universitas Indonesia; 2007.
Song SJ, Lee JE, Paik HY, Park MS, Song YJ. Dietary patterns based on carbohydrate nutrition are associated with the risk for diabetes and dyslipidemia. Nutr Res Pract. 2012 Aug;6(4):349–56.
Volek JS, Fernandez ML, Feinman RD, Phinney SD. Dietary carbohydrate restriction induces a unique metabolic state positively affecting atherogenic dyslipidemia, fatty acid partitioning, and metabolic syndrome. Vol. 47, Progress in Lipid Research. 2008. p. 307–18.
Mensink RP. Effects of saturated fatty acids on serum lipids and lipoproteins: a systematic review and regression analysis.
Liu Y, Zhang P, Wang W, Wang H, Zhang L, Wu W, et al. The characteristics of dyslipidemia patients with different durations in Beijing: A cross-sectional study. Lipids Health Dis. 2010;9.
Christian AH, Mochari H, Mosca LJ. Waist circumference, body mass index, and their association with cardiometabolic and global risk. J Cardiometab Syndr. 2009;4(1):12–9.
Carr MC, Brunzell JD. Abdominal obesity and dyslipidemia in the metabolic syndrome: Importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk. In: Journal of Clinical Endocrinology and Metabolism. 2004. p. 2601–7.
Halperin RO, Sesso HD, Ma J, Buring JE, Stampfer MJ, Gaziano JM. Dyslipidemia and the risk of incident hypertension in men. Hypertens (Dallas, Tex 1979) [Internet]. 2006 Jan [cited 2020 Jan 9];47(1):45–50. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16344375
Papathanasopoulos A, Camilleri M. Dietary Fiber Supplements: Effects in Obesity and Metabolic Syndrome and Relationship to Gastrointestinal Functions. Gastroenterology [Internet]. 2010;138(1):65-72.e2. Available from: http://dx.doi.org/10.1053/j.gastro.2009.11.045
Lauralee Sherwood. Fisiologi Manusia dari Sel ke Sistem. 2nd ed. Jakarta: Penerbit Buku Kedokteran EGC.; 2001.
Chandola T, Britton A, Brunner E, Hemingway H, Malik M, Kumari M, et al. Work stress and coronary heart disease: what are the mechanisms? Eur Heart J [Internet]. 2008 Mar 1 [cited 2020 Jan 8];29(5):640–8. Available from: https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehm584
Kokkinos P. Physical activity and cardiovascular disease prevention: Current recommendations. Angiology. 2008;59(2_suppl):26S-29S.
DOI: https://doi.org/10.47007/nut.v12i01.3014
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